Book Chapters


Melo R, Lemos A, Preto AJ, Almeida JG, Correia JDG, Sensoy O, Moreira IS. Computational Approaches in Antibody-drug Conjugate Optimization for Targeted Cancer Therapy. Curr Top Med Chem. 2018;18(13):1091-1109. doi: 10.2174/1568026618666180731165222. Review.

Moreira IS, Sensoy O. Modulation of Protein-Protein Interactions for the Development of Effective Therapeutics – From a Joint Perspective of Experiment and Computation. Curr Top Med Chem. 2018;18(8):645-646. doi: 10.2174/156802661808180718151704.

Schiedel AC, Kose M, Barreto C, Bueschbell B, Morra G, Sensoy O, Moreira IS. Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers. Curr Top Med Chem. 2018;18(8):714-746. doi: 10.2174/1568026618666180604082610. Review.

A.J. Preto, J.G. Almeida, J. Schaarschmidt, L.C. Xue, I.S. Moreira and A.M.J.J. Bonvin. Computational tools for the structural characterization of proteins and their complexes from sequence-evolutionary data. Encyclopedia of Analytical Chemistry, 2018.

Lemos A, Melo R, Preto AJ, Almeida JG, Moreira IS, Dias Soeiro Cordeiro MN. In Silico Studies Targeting G-protein Coupled Receptors for Drug Research Against Parkinson’s Disease. Curr Neuropharmacol. 2018;16(6):786-848. doi: 10.2174/1570159X16666180308161642.


Lemos A, Melo R, Moreira IS, Cordeiro MNDS, Computational approaches to target key therapeutical targets in Alzheimer disease, in Neuromethods, ed. Kunal Roy, Springer, 2017, 61-106.

Sensoy O, Almeida JG, Shabbir J, Moreira IS, Morra G, Computational modeling – a way to understand GPCR structure, function and mechanism, in Methods in Cell Biology, 2017,  205-245.


Moreira IS, Bras NB, Carvalho A, Cerqueira NMFSA, Dourado DF, Perez MAS,. Ribeiro AJM, Sousa SF, Fernandes PA, Ramos MJ, Computational proteomics – from methodological developments to biological applications, In book: Quantal Aspects in Chemistry and Physics : A tribute to the memory of Professor Couceiro da Costa, Publisher: Imprensa da Universidade de Coimbra, Editors: J. S. Redinha J. da Providência A. J. C. Varandas, pp.181-220.


Moreira IS, Shi L, Freyberg Z., Eriksen S. S., Weinstein H, Javitch J, Structural Basis of Dopamine Receptor Activation and Function in The Dopamine Receptors, ed Kim Neve, Humana/Springer, 2010, 47-73.


Moreira IS, Fernandes PA, Computational Alanine Scanning Mutagenesis in Computational Proteomics, ed Maria J. Ramos, Transworld Research Network, 2008.


Moreira IS, Fernandes PA, Ramos MJ, computational Determination of the Relative Free Energy of Binding – Application to Alanine Scanning Mutagenesis in Molecular Materials with Specific Interactions: Modeling and Design, ed W.Andrzej Sokalski, Springer, 2007, 305-340.